Do we really need spironolactone to meke our transgender bodies feminine
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However, in contrast to many other steroid esters hydrolysis is not extensive, and much of the pharmacological activity is exerted by the acetate form. This combination suggests that transsexual men are at higher risk of cardiovascular disease. Reproductive system and breast disorders. How did you know what to take and the dosage required? The combined doses of anti-androgens are above normal. A general approach for titration would include increasing of both estrogen and antiandrogen dosing until the estrogen dose is in the female physiologic range.
This article compares recommendations from medical and non-medical sources, and explains conditions that could result from HRT, whether therapy is medically monitored or not. This information is not provided or intended as a substitute for professional medical advice or care.
I am not a medical professional. Please also note that the glossary at the end of this article is just that: The descriptions of the terms in the glossary are meant to help you interpret their use in this article only, and are not comprehensive definitions. Because the populations are so different, this article is arranged in two sections, one reporting on MTFs and one on FTMs.
There are no generally agreed upon recommended dosages, or recommended drugs within categories.
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Cyproterone acetate CPA Prohibition, sold alone out of sight the brand stage name Androcur or with ethinylestradiol under the brand names Diane or Diane lot others, is an antiandrogen and progestin medication which is used in the treatment of androgen-dependent conditions like acne , excessive hair's breadth growth , betimes puberty , and prostate cancer Herself, as a component of feminizing hormone therapy for transgender women , and in birth hold sway over pills. CPA is taken by d�bouch� one to three times per age and is premised by injection instantly or twice per week.
Common side effects of high-dose CPA in men include gynecomastia boob development and feminization. In both men and women, side effects of CPA include low shagging hormone levels Detracting, reversible infertility Largely, sexual dysfunction Edict, mental symptoms cognate depression , listlessness , and irritability , vitamin B12 deficiency , and elevated liver enzymes. At very capital doses, cardiovascular complications can occur.
Rare but serious adverse reactions of CPA include blood clots , liver mutilate , and valid types of propitious brain tumors. CPA can also promote adrenal insufficiency as a withdrawal operational if it is discontinued abruptly from a high dosage. CPA blocks the effects of androgens like testosterone in the body, which it does through preventing them from interacting with their biological target Regular, the androgen receptor AR , and by reducing their production by the gonads and in the future their concentrations in the body.
CPA was discovered in CPA is used as a progestin and antiandrogen in hormonal lineage control and in the treatment of androgen-dependent conditions. In the United States, where CPA is not available, other medications with antiandrogenic effects are toughened to treat androgen-dependent conditions instead.
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Interpretation of laboratory results requires special attention in the context of transgender care. This article is literally from and was poorly researched, at that. The Journal of Clinical Endocrinology and Metabolism. Is that dose good enough to begin with? CPA is useful in the treatment of hot flashes , for instance due to androgen deprivation therapy.
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Calls But Doesn't Talk?of the United States cyproterone acetate, also known as Androcur, is the preferred drug. Outside of transgender care it's also used for prostate cancer, as The dose often used for transition in the literature is mg/day. Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol Common side effects of high-dose CPA in men include gynecomastia (breast development) and feminization. .. As the antiandrogen component of transgender HRT, treatment with CPA (as well as with spironolactone to a..
- Our objective was to determine whether CPA at 25 mg daily would suppress total testosterone as effectively...
- It is usually the focus of hormonal transition for trans women. The starting dose of estrogen...
-  Doses of mg daily in non-transgender women being treated...
- CYPROTERONE (ANDROCUR) GONE BAD
- CYPROTERONE ACETATE (CPA), SOLD ALONE UNDER THE BRAND NAME ANDROCUR OR WITH ETHINYLESTRADIOL COMMON SIDE EFFECTS OF HIGH-DOSE CPA IN...
- ANYONE KNOW ABOUT ANDROCUR? : ASKTRANSGENDER
- CYPROTERONE ACETATE - WIKIPEDIA
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